Carbohydrate diabetic diet high
Inclusion criteria were an age of at least 18 years and a body-mass index (the weight in kilograms divided by the square of the height in meters) of at least 35. Low-carbohydrate, high-protein, high-fat diets have become increasingly popular, and many best-selling diet books have promoted this approach. Methods We conducted a one-year, multicenter, controlled trial involving 63 obese men and women who were randomly assigned to either a low-carbohydrate, high-protein, high-fat diet or a low-calorie, high-carbohydrate, low-fat (conventional) diet. This finding should be interpreted with caution, given the small magnitude of overall and between-group differences in weight loss in these markedly obese subjects and the short duration of the study. Methods Subjects The study was approved by the institutional review board at the Philadelphia Veterans Affairs Medical Center, and an approved consent form was signed by each subject. Article Activity 517 articles have cited this article Article The differences in health benefits between a carbohydrate-restricted diet and a calorie- and fat-restricted diet are of considerable public interest. Longer and larger studies are required to determine the long-term safety and efficacy of low-carbohydrate, high-protein, high-fat diets. Future studies evaluating long-term cardiovascular outcomes are needed before a carbohydrate-restricted diet can be endorsed. Conclusions Severely obese subjects with a high prevalence of diabetes or the metabolic syndrome lost more weight during six months on a carbohydrate-restricted diet than on a calorie- and fat-restricted diet, with a relative improvement in insulin sensitivity and triglyceride levels, even after adjustment for the amount of weight lost. The subjects were randomly assigned to follow either a low-carbohydrate, high-protein, high-fat Atkins diet or a high-carbohydrate, low-fat, energy-deficit conventional diet. Methods We randomly assigned 132 severely obese subjects (including 77 blacks and 23 women) with a mean body-mass index of 43 and a high prevalence of diabetes (39 percent) or the metabolic syndrome (43 percent) to a carbohydrate-restricted (low-carbohydrate) diet or a calorie- and fat-restricted (low-fat) diet.
Both diets significantly decreased diastolic blood pressure and the insulin response to an oral glucose load. Abstract Background Despite the popularity of the low-carbohydrate, high-protein, high-fat (Atkins) diet, no randomized, controlled trials have evaluated its efficacy. Adherence was poor and attrition was high in both groups. During an enrollment period that lasted from May to November 2001, 132 subjects from the Philadelphia Veterans Affairs Medical Center were randomly assigned to either the low-carbohydrate diet or the low-fat diet, with use of a preestablished algorithm generated from a random set of numbers. The low-carbohydrate diet was associated with a greater improvement in some risk factors for coronary heart disease. 8,9 The Atkins diet, originally published in 1973 and again in 1992 and 2002, may be the most popular of these diets. Professional contact was minimal to replicate the approach used by most dieters. Abstract Background The effects of a carbohydrate-restricted diet on weight loss and risk factors for atherosclerosis have been incompletely assessed. Figure 2 Percentage of Subjects with a Positive Urinary Ketone Concentration, According to Whether They Were on the Low-Carbohydrate Diet or the Conventional (Low-Calorie, High-Carbohydrate) Diet. Conclusions The low-carbohydrate diet produced a greater weight loss (absolute difference, approximately 4 percent) than did the conventional diet for the first six months, but the differences were not significant at one year. The increase in high-density lipoprotein cholesterol concentrations and the decrease in triglyceride concentrations were greater among subjects on the low-carbohydrate diet than among those on the conventional diet throughout most of the study.
